Review and Progress

The Diagnosis and Treatment of Breast Invasive Lobular Carcinoma  

Li W.Q.1 , Zhai Z.W.1 , Guo Z.F.1 , Zhang D.W.1,2
1 The Second Hospital of Harbin Medical University, Harbin, 150081, China
2 Heilongjiang Academy of Medical Sciences, Harbin, 150081, China
Author    Correspondence author
Cancer Genetics and Epigenetics, 2017, Vol. 5, No. 1   doi: 10.5376/cge.2017.05.0001
Received: 04 Jan., 2017    Accepted: 05 Jan., 2017    Published: 05 Jan., 2017
© 2017 BioPublisher Publishing Platform
This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Preferred citation for this article:

Li W.Q., Zhai Z.W., Guo Z.F., and Zhang D.W., 2017, The diagnosis and treatment of breast invasive lobular carcinoma, Cancer Genetics and Epigenetics, 5(1): 1-5 (doi: 10.5376/cge.2017.05.0001)


Invasive lobular carcinoma of the breast to breast cancer cells in the breakthrough of mammary gland flocculus endings tube or to lobular acini basement membrane mesenchymal invasive growth as the main characteristics.Breast invasive lobular carcinoma usually has a better prognosis of phenotype, low-level histological grade, low  mitotic index, hormone receptor-positive,its her-2 negative, P53, low, lack of calcium mucin, sensitivity to endocrine therapy.Tended to be older patients diagnosis, tumor larger, axillary lymph node metastasis rate is higher, when a side breast invasive lobular carcinoma, the contralateral tend to occur.Invasive lobular carcinoma invasive is strong, has extensive transfer value tendency, therefore, in some studies in comparison with other invasive carcinoma with poor prognosis.

Invasive lobular carcinoma; Immunohistochemistry and molecular biology; Comprehensive treatmen
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