Review and Progress
The Diagnosis and Treatment of Breast Invasive Lobular Carcinoma
1 The Second Hospital of Harbin Medical University, Harbin, 150081, China
2 Heilongjiang Academy of Medical Sciences, Harbin, 150081, China
Cancer Genetics and Epigenetics, 2017, Vol. 5, No. 1 doi: 10.5376/cge.2017.05.0001
Received: 04 Jan., 2017 Accepted: 05 Jan., 2017 Published: 05 Jan., 2017
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This is an open access article published under the terms of the Creative Commons Attribution License
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Preferred citation for this article:
Li W.Q., Zhai Z.W., Guo Z.F., and Zhang D.W., 2017, The diagnosis and treatment of breast invasive lobular carcinoma, Cancer Genetics and Epigenetics, 5(1): 1-5 (doi: 10.5376/cge.2017.05.0001)
Invasive lobular carcinoma of the breast to breast cancer cells in the breakthrough of mammary gland flocculus endings tube or to lobular acini basement membrane mesenchymal invasive growth as the main characteristics.Breast invasive lobular carcinoma usually has a better prognosis of phenotype, low-level histological grade, low mitotic index, hormone receptor-positive,its her-2 negative, P53, low, lack of calcium mucin, sensitivity to endocrine therapy.Tended to be older patients diagnosis, tumor larger, axillary lymph node metastasis rate is higher, when a side breast invasive lobular carcinoma, the contralateral tend to occur.Invasive lobular carcinoma invasive is strong, has extensive transfer value tendency, therefore, in some studies in comparison with other invasive carcinoma with poor prognosis.
Invasive lobular carcinoma; Immunohistochemistry and molecular biology; Comprehensive treatmen
Cancer Genetics and Epigenetics
• Volume 5