A Letter

A Rare Case of Plexiform Schwannoma Involving Cerebellopontine Angle  

Yafang Dou , Zonghui Liang
Department of radiology, Jing’an District Center Hospital of Fudan University, No.259, Xikang Road, Shanghai, China
Author    Correspondence author
Cancer Genetics and Epigenetics, 2017, Vol. 5, No. 5   doi: 10.5376/cge.2017.05.0005
Received: 05 Dec., 2017    Accepted: 13 Dec., 2017    Published: 29 Dec., 2017
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Preferred citation for this article:

Dou Y.F. and Liang Z.H., 2017, A rare case of plexiform schwannoma involving cerebellopontine angle, Cancer Genetics and Epigenetics, 5(5): 25-27 (doi: 10.5376/cge.2017.05.0005)


Plexiform schwannoma (PS) is an infrequent variety of benign nerve sheath tumor characterized by multi-nodular (plexiform) architecture and the individual thin capsule. The pre-operative diagnosis of PS is difficult. In this report, we describe a case of PS presented in the cerebellopontine angle (CPA) space. Our case involved a 32-year-old woman with one-month history of worsening verbal vagueness associated with unstable gait. MRI revealed a solid-cystic mass with in the left CPA region. The mass was resected completely, and the diagnosis of PS was confirmed by histopathology. While schwannoma commonly occurs in the head and neck, CPA space PS is rare, and pre-operative pathological diagnosis of PS is difficult. MRI studies of PS revealed distinctive features that we found useful in pre-operative diagnosis.

Plexiform schwannoma; Cerebellopontine angle; Diagnosis; MRI
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