Research Article

Growth Performance, Blood Profile, Organosomatic Indices and Histopathology of Clarias gariepinus Fed Amoxicillin as Dietary Additive  

Adewole AdeyemoMuniru
Department of Animal and Environmental Biology, AdekunleAjasin University, PMB 001, AkungbaAkoko, Ondo State, Nigeria
Author    Correspondence author
International Journal of Aquaculture, 2016, Vol. 6, No. 15   doi: 10.5376/ija.2016.06.0015
Received: 15 Aug., 2016    Accepted: 10 Nov., 2016    Published: 28 Dec., 2016
© 2016 BioPublisher Publishing Platform
This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Preferred citation for this article:

Adewole A.M., 2016, Growth performance, blood profile, organosomatic indices and histopathology of Clarias gariepinus fed amoxicillin as dietary additive, International Journal of Aquaculture, 6(15): 1-13 (doi: 10.5376/ija.2016.06.0015)

Abstract

A 12 week feeding trial was conducted to investigate the effect of administration of different dosages of amoxicillin on biophysiological responses: nutritional, haematological, serum biochemical, organosomatic indices and histopathological study of juvenile Clarias gariepinus. One hundred and eighty juvenile C. gariepinus with the mean weight of 10.94 ± 0.01 g were stocked into the different treatments using a completely randomized design. The fishes were fed diets containing iso-nitrogenous crude protein (40%) at 5% body weight, twice a day. Histopathological results showed no visible lesions in some of the tissues of the fish fed with control and amoxicillin diets. However, there were marked pathological conditions that were manifested in some organs like the liver, brain, kidney and intestine of fish. The inclusion of amoxicillin at 0.5% in the diet of C. gariepinus is being advocated in sustainable catfish production in Nigeria.

Keywords
Amoxicillin; Biophysiological; Clarias gariepinus
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International Journal of Aquaculture
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