Department of Endocrine and Metabolic diseases, Bab El Oued Hospital, Algiers, Algeria
International Journal of Clinical Case Reports, 2015, Vol. 5, No. 10 doi: 10.5376/ijccr.2015.05.00010
Received: 17 Dec., 2014 Accepted: 17 Jan., 2015 Published: 27 Feb., 2015
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Preferred citation for this article:
Azzoug et al., 2015, Malignant insulinoma, International Journal of Clinical Case Reports, Vol.5, No. 10 1-3 (doi: 10.5376/ijccr.2015.05.0010)
Malignant insulinomas are rare representing 4-14% of insulinomas with poor prognosis. Diagnosis of malignancy relies on the presence of lymph node or distant metastasis. Clinical manifestations of malignant insulinomas are similar but are more severe and frequent to those of benign insulinomas characterized by clinical hypoglycemic signs with predominance of neuroglucopenic symptoms. Surgical removal of the tumor and eventually metastasis is the corn stone of the treatment, other therapeutic modalities and anti-secretion drugs are complementary treatments. In this study we report the observations of three malignant insulinomas.
Malignant insulinoma; Hypoglycemia; Surgery; Anti-secretion drugs
International Journal of Clinical Case Reports
• Volume 5