Etiologies of Central Diabetes Insipidus in Children  

Said Azzoug , Mourad Kesraoui , Farida Chentli
Endocrinological Department Bab El Oued Hospital, Algiers, Algeria
Author    Correspondence author
International Journal of Clinical Case Reports, 2015, Vol. 5, No. 17   doi: 10.5376/ijccr.2015.05.0017
Received: 07 Feb., 2015    Accepted: 27 Mar., 2015    Published: 23 Apr., 2015
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Preferred citation for this article:

Azzoug et al., 2015, Etiologies of Central Diabetes Insipidus in Children, International Journal of Clinical Case Reports, Vol.5, No.17 1-2 (doi: 10.5376/ijccr.2015.05.0017)


Background Central diabetes insipidus is a heterogeneous disease mainly due to lesions of hypothalamic nuclei or pituitary stalk caused by tumors of the suprasellar region or infiltrative diseases such as Langerhans cells histiocytosis or sarcoidosis.

Objective: The aim of our study was to analyze the etiologies of central diabetes insipidus in children.
Methods: Medical records of 31 children (mean age of 7 years) were reviewed.

Results Craniopharyngioma was the main etiology found in 71%, in 3.2% diabetes insipidus was secondary to autoimmune hypophysitis, in 3.2% it appears after radiotherapy for a germinoma of the pineal region, finally, in 22.6% it was considered as idiopathic.
Diabetes insipidus; Craniopharyngioma; Hypophysitis; Germinoma
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