Juvenile Hyperthyroidism  

Said Azzoug , Farida Chentli
Endocrine diseases department Bab El Oued Hospital Algiers, Algeria
Author    Correspondence author
International Journal of Clinical Case Reports, 2015, Vol. 5, No. 36   doi: 10.5376/ijccr.2015.05.0036
Received: 05 Jul., 2015    Accepted: 06 Aug., 2015    Published: 08 Sep., 2015
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Preferred citation for this article:

Azzoug S. and Chentli F., 2015, Juvenile Hyperthyroidism, International Journal of Clinical Case Reports, 5(36) 1-2 (doi: 10.5376/ijccr.2015.05.0036)

Abstract

Background: Hyperthyroidism is less frequent in children than adults and its clinical profile is different.
Objective: The objective of our study was to analyze the clinical characteristics of hyperthyroidism in children and adolescents.

Subjects and Methods: It is a retrospective study concerning 161 patients (129 Females/32 Males) with mean age of 15.63 ± 3.51 years. Their medical records were reviewed.

Results: 98.1% have Graves’ disease. Appealing symptoms were thyrotoxicosis signs in 69%, ophtalmological signs in 15% and goiter in 16%. Diagnosis delay was of 20.73±20.69 months. Clinical presentation was obvious in 81% and discrete in 19%. Goiter was of type II/type III in 74% and of type I in 26%, exophtalmous was present in 69% and it was severe in 12.5%. Several complications were recorded, cardiothyreosis in 1.86%, dysglycemia in 13.04%, myopathy in 3.72% and behavioral disorders in 6.83%.

Conclusion: Graves’ disease is the main etiology of hyperthyroidism in children and adolescents; diagnosis is often delayed although it is clinically obvious so complications may occur. Therefore hyperthyroidism should be diagnosed and treated promptly.

Keywords
Juvenile hyperthyroidism; Graves’ disease; Thyrotoxicosis; Goiter
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