Phenotypic and Evolutionary Characteristics of Precocious Puberty: About 30 Cases
1.Department of Endocrinology, EPH Bologhine Algiers, Algeria
2.Department of Endocrinology, CHU BEO Algiers, Algeria
International Journal of Clinical Case Reports, 2015, Vol. 5, No. 49 doi: 10.5376/ijccr.2015.05.0049
Received: 21 Jul., 2015 Accepted: 22 Aug., 2015 Published: 10 Dec., 2015
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Preferred citation for this article:
Fedala S.N., Chentli F., Meskine D., Haddam A.E.M., 2015, Phenotypic and Evolutionary Characteristics of Precocious Puberty: About 30 Cases, International Journal of Clinical Case Reports, 5(49) 1-5 (doi: 10.5376/ijccr.2015.05.0049)
Thirty children with precocious puberty (PP) were followed in Endocrinology department, from 2000 to 2015. The disorder was more common in girls than in boys with a sex ratio (F/M) of 3.
The mean age at diagnosis was 4.2 ± 1.4 years (1-8.5) in girls and 5.6 ± 1.4 years (17 months - 9 years) in boys. The average delay for consultation, relative to the ascertainment of the first sign of that early puberty is 2.5 years (6 months - 6 years) in girls and 3.2 years (6 months - 4 years) in boys.
The PP was scalable for all boys and half of girls (52.5%). Pubertal precocity was of central origin (CPP) in 83% of girls and in 70% of cases it was idiopathic. In boys organic cause was noted in all of them, it was central in 28.5%. The peripheral origin noted in 72% of cases is related to a congenital adrenal hyperplasia.
Precocious puberty; Secondary sexual characteristics; Brain MRI; Congenital adrenal hyperplasia; Hypothalamic hamartoma