A Letter

Allgrove Syndrome: A little Common Clinical Presentation  

M. A. Amani , S.  Miraoui
Department of Endocrinology and Diabetology 1st November Hospital Oran, Algeria
Author    Correspondence author
International Journal of Clinical Case Reports, 2016, Vol. 6, No. 18   doi: 10.5376/ijccr.2016.06.0018
Received: 22 Feb., 2016    Accepted: 28 Mar., 2016    Published: 08 Aug., 2016
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Preferred citation for this article:

M. A. Amani, and S. Miraoui, 2016, Allgrove syndrome: A Little Common Clinical Presentation, International Journal of Clinical Case Report, 6(16): 1-3 (doi: 10.5376/ijccr.2016.06.0016)

The Allgrove syndrome or triple A is a rare inherited autosomal recessive syndrome. The presence of the clinical triad type alacrima, achalasia and Addison's disease is sufficient for the diagnosis. We report the case of a family, the sister and the brother, respectively 11 and 19 years old, from a 1st degree consanguineous marriage and who presented the characteristic signs of the Allgrove syndrome with 2 features: a growth hormone deficiency for the sister and congenital bone malformations for the brother. To our knowledge these characteristics have not been described previously.
Allgrove syndrome; Achalasia; Alacrima; Adrenal insufficiency; Growth hormone deficiency; Congenital bone malformations
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