Allgrove Syndrome: A little Common Clinical Presentation
M. A. Amani
Department of Endocrinology and Diabetology 1st November Hospital Oran, Algeria
International Journal of Clinical Case Reports, 2016, Vol. 6, No. 18 doi: 10.5376/ijccr.2016.06.0018
Received: 22 Feb., 2016 Accepted: 28 Mar., 2016 Published: 08 Aug., 2016
© 2016 BioPublisher Publishing Platform
This is an open access article published under the terms of the Creative Commons Attribution License
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Preferred citation for this article:
M. A. Amani, and S. Miraoui, 2016, Allgrove syndrome: A Little Common Clinical Presentation, International Journal of Clinical Case Report, 6(16): 1-3 (doi: 10.5376/ijccr.2016.06.0016)
The Allgrove syndrome or triple A is a rare inherited autosomal recessive syndrome. The presence of the clinical triad type alacrima, achalasia and Addison's disease is sufficient for the diagnosis. We report the case of a family, the sister and the brother, respectively 11 and 19 years old, from a 1st degree consanguineous marriage and who presented the characteristic signs of the Allgrove syndrome with 2 features: a growth hormone deficiency for the sister and congenital bone malformations for the brother. To our knowledge these characteristics have not been described previously.
Allgrove syndrome; Achalasia; Alacrima; Adrenal insufficiency; Growth hormone deficiency; Congenital bone malformations
International Journal of Clinical Case Reports
• Volume 6