Case Report

Surgical Management of Endo-Perio Lesion with Demineralised Bone Matrix in Combination with Platelet Rich Fibrin: A Case Report  

Pradnya Kale1 , Kamlesh Talesara2 , Kaustubh P. Patil3 , Abhishek Singh Nayyar4
1 Department of Conservative Dentistry & Endodontics, Dr.D.Y.Patil Dental College & Hospital, Pune, Maharashtra, India
2 Department of Periodontics and Oral Implantology, Dr.D.Y.Patil Dental School, Lohegaon, Pune, Maharashtra, India
3 Department of Periodontics and Oral Implantology, Dr.D.Y.Patil Dental College & Hospital, Pune, Maharashtra, India
4 Department of Oral Medicine and Radiology, Saraswati-Dhanwantari Dental College and Hospital and Post-Graduate Research Institute, Parbhani, Maharashtra, India
Author    Correspondence author
International Journal of Clinical Case Reports, 2016, Vol. 6, No. 22   doi: 10.5376/ijccr.2016.06.0022
Received: 13 May, 2016    Accepted: 19 Aug., 2016    Published: 22 Aug., 2016
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This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Preferred citation for this article:

Pradnya K., Kamlesh T., Kaustubh P.P., and Abhishek S.N., 2016, Surgical management of Endo-Perio lesion with demineralised bone matrix in combination with platelet rich fibrin: A Case Report, International Journal of Clinical Case Report, 6(22): 1-8 (doi: 10.5376/ijccr.2016.06.0022)


Periodontal disease is a chronic inflammatory disease process that eventually leads to loss of periodontal attachment and an eventual, bone destruction. The objective of periodontal therapy is to regenerate the lost periodontal tissues. Platelets are rich in growth factors that may contribute to an accelerated process of tissue regeneration. Demineralised bone matrix, (DMBM) xenograft is a bone inductive, sterile, bioresorbable, graft composed of Type I collagen. Given the unique properties of autologous platelet rich fibrin (PRF) and already demonstrated regenerative capacity of commercially available bone grafts, application of a combination approach was attempted. We herewith present a case report of a combined endo-perio lesion that was treated by a combination of autologous PRF and bovine derived xenograft, assessed clinically and radiographically.

Periodontal disease; Periodontal therapy; Demineralised bone matrix; Xenograft; Platelet rich fibrin; Bone grafts
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