Pharmacology and Clinical Use of Dimethyl Sulfoxide (DMSO): A Review  

Patil Manjunath , B.V. Shivaprakash
Krishi Vigyan Kendra, Aland road, Gulbarga, UAS, Raichur, Karnataka, India-585 101
Author    Correspondence author
International Journal of Molecular Veterinary Research, 2013, Vol. 3, No. 6   doi: 10.5376/ijmvr.2013.03.0006
Received: 27 Mar., 2013    Accepted: 11 Apr., 2013    Published: 20 Aug., 2013
© 2013 BioPublisher Publishing Platform
This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Preferred citation for this article:

Manjunath and Shivaprakash, 2013, Pharmacology and Clinical Use of Dimethyl Sulfoxide (DMSO): A Review, International Journal of Molecular Veterinary Research, Vol.3, No.6 23-33 (doi: 10.5376/ ijmvr.2013.03.0006)

Abstract

Dimethyl sulfoxide is having a pyramidal structure, CH3-SO-CH3. It is a dipolar, aprotic and highly hygroscopic solvent. It readily penetrates the skin within 5 minutes after cutaneous application. It enhances penetration of Anaesthetic, cardioactive, anticholinesterase and other not-innocuous therapeutic agents. It is recommended for acute sprains, strains, bursitis and their associated soft tissue swellings and haematoma. Combination therapy of DMSO with antibiotics or steroids enhance the healing of cutaneous habronemiasis or summer sores, bumble foot, acral lick dermatitis ,arthritis, and mastitis. It is considered to have a low toxicity. Chronic thermal, chemical exposure of DMSO solvent and higher levels of chemical contaminants with severe electrical burns causes the invasive squamous cell carcinoma of the upper extremities in human beings. The therapeutic intravenous dose is about 1.0 g/kg in 10~45% solution administered slowly in humans, cats, dogs and horses. Intra articular administration of DMSO reduced severity of chemically induced synovitis in horses.

Keywords
Pharmacology; Dimethyl sulfoxide (DMSO); Radioscavenging property; Therapeutic applications
[Full-Text PDF] [Full-Flipping PDF] [Full-Text HTML]
International Journal of Molecular Veterinary Research
• Volume 3
View Options
. PDF(118KB)
. FPDF
. HTML
. Online fPDF
Associated material
. Readers' comments
Other articles by authors
pornliz suckporn sex videos bbw mom xxx big fucking arabin porn videos teen gril sex video riding hard cock woman hard vagina . Patil Manjunath
. B.V. Shivaprakash
Related articles
. Pharmacology
. Dimethyl sulfoxide (DMSO)
. Radioscavenging property
. Therapeutic applications
Tools
. Email to a friend
. Post a comment