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New Biosynthetic Pathway Unique to Pathogenic Microorganisms | A Bioscience Publishing Platform
New Biosynthetic Pathway Unique to Pathogenic Microorganisms
Published:14 Jul.2017    Source:Science Daily

A new unique biosynthetic pathway for D-Glutamate has been discovered, an important cell wall component in pathogenic bacteria, which could lead to the development of medicines and agricultural chemicals. D-Glu is supplied by an enzyme called Glu racemases. The newly discovered pathway involves two genes which facilitate the binding of L-Glu to UDP-MurNAc-L-Ala and then epimerize (isomerize) L-Glu to D-Glu.