Research Article

Morphological Changes in the Digestive System of Aedes aegypti L. Induced by [Cu(EDTA)]2- Complex Ions  

Cleusa Rocha Garcia Gaban1 , Eduardo José de Arruda2 , Doroty Mesquita Dourado3 , Lilliam May Grespan E. da Silva1 , Paulo César Cavalcante Vila Nova1 , Isaías Cabrini2,4
1. Chemistry, Federal University of Mato Grosso do Sul, Campo Grande, MS, Brazil
2. Chemistry, Faculty of Exact Sciences and Technology - FACET, Federal University of Grande Dourados, Dourados, Brazil
3. Biology, Anhanguera/UNIDERP, Campo Grande, MS, Brazil
4. State University of Campinas, Institute of Biology, Department of Animal Biology, Brazil
Author    Correspondence author
Journal of Mosquito Research, 2015, Vol. 5, No. 21   doi: 10.5376/jmr.2015.05.0021
Received: 16 Sep., 2015    Accepted: 04 Nov., 2015    Published: 24 Nov., 2015
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This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Preferred citation for this article:

Gaban C.R.G., de Arruda E.J., Dourado D.M., da Silva L.M.G.E., Nova P.C.C.V., and Cabrini I., 2015, Morphological Changes in the Digestive System of Aedes aegypti L. Induced by [Cu(EDTA)]2- Complex Ions, Journal of Mosquito Research, 5(21): 1-9 (doi: 10.5376/jmr.2015.05.0021)

Although insecticides are important tools for the control of disease vectors, their loss effectiveness and associated environmental problems have led to research aimed at discovering or designing new active principles. However, little is known about the physiological effects of new insecticides. Using histopathological techniques, this study elucidates the morphological changes that occur in the midgut of Aedes aegypti larvae after treatment with the metal complex [Cu(EDTA)]2-. The midgut was the most heavily affected part of the larvae. Cell debris was found in the lumen of the digestive system, a sign of the total destruction of insect tissue, specifically the destructive vacuolization of columnar and regenerative intestinal cells. The apical surfaces of the columnar cells exhibited oriented projections into the lumen, suggesting that these cells are involved in apoptosis. These results are an important supplement to the analysis and development of larvicides based on metal complexes, and will facilitate the design of effective Aedes aegypti control strategies.
Metal complex; Metallo-insecticide; Mosquito; Toxicity
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pornliz suckporn sex videos bbw mom xxx big fucking arabin porn videos teen gril sex video riding hard cock woman hard vagina . Cleusa Rocha Garcia Gaban
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