Research Report

Laboratory Study on the Repellent Bioefficacy of Diethyl Phenyl Acetamide (DEPA) against Aedes (Stegomyia) aegypti (Linnaeus)  

Chee Dhang Chen1 , Othman Wan-Norafikah2, 3 , Koon Weng Lau1 , Han Lim Lee4 , Chong Chin Heo2 , Cherng Shii Leong1 , Mohd Sofian-Azirun1
1 Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia
2 Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh Campus, Jalan Hospital, 47000 Sungai Buloh, Selangor, Malaysia
3 HW Core, Universiti Teknologi MARA, 40450 Shah Alam, Selangor, Malaysia
4 Medical Entomology Unit and WHO Collaborating Centre for Vectors, Infectious Diseases Research Centre, Institute for Medical Research, Jalan Pahang, 50588 Kuala Lumpur, Malaysia
Author    Correspondence author
Journal of Mosquito Research, 2017, Vol. 7, No. 2   doi: 10.5376/jmr.2017.07.0002
Received: 23 Dec., 2016    Accepted: 04 Feb., 2017    Published: 10 Feb., 2017
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This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Preferred citation for this article:

Chen C.D., Wan-Norafikah O., Lau K.W., Lee H.L., Heo C.C., Leong C.S., and Sofian-Azirun M., 2017, Laboratory study on the repellent bioefficacy of diethyl phenyl acetamide (DEPA) against Aedes (Stegomyia) aegypti (Linnaeus), Journal of Mosquito Research, 7(2): 9-14 (doi: 10.5376/jmr.2017.07.0002)


Insect repellent has played an important role in preventing humans from insect bites. This study was conducted to evaluate the repellency effect of a repellent cream containing 20% w/v diethyl phenyl acetamide (DEPA) against Aedes aegypti. DEET (10% w/v) was used as a standard repellent in comparison with DEPA. The test procedures followed the bioassay methods of Standards and Industrial Research Institute of Malaysia (SIRIM). There was statistically no significant difference between the repellency activity of both repellents (p>0.05), indicating the repellent cream of DEPA was as effective as DEET. Treatment with both repellent cream provided 8 hours of protection, with more than 60% reduction of mosquito landing on the skin.

Diethyl phenyl acetamide (DEPA); N,N-diethyl-meta-toluamide (DEET); Aedes aegypti; Mosquito repellent; Reduction of mosquito bites
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