trafik ceza easy agario agario games agario agario unblocked agario modded agarioprivate An Outer Membrane Vesicle Vaccine against Meningococcal Disease in Guangxi Province | Huang | Journal of Vaccine Research

An Outer Membrane Vesicle Vaccine against Meningococcal Disease in Guangxi Province  

Qingxu Huang , Junyu Lu
Yulin Normal University, Biology Department, Yulin, 537000, P.R. China
Author    Correspondence author
Journal of Vaccine Research, 2014, Vol. 4, No. 1   
Received: 10 Jun., 2014    Accepted: 12 Aug., 2014    Published: 19 Nov., 2014
© 2014 BioPublisher Publishing Platform
This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

An outer membrane vesicle vaccine against acute, systemic disease caused by meningococci of serogroup B has been developed. The vaccine has been tested consecutively in phase I and phase II clinical trials including more than 3 000 volunteers. These trials provided data on safety, immunogenicity and reactogenicity and possible effect on carriage of meningococci in the throat, and consequently formed the basis for two major protection trials; one in secondary school students and one among military recruits. The aims, design and major results of phase I and phase II studies are described as well as the design and organization of the protection trials.

Outer membrane vesicle vaccine; Meningococcal disease; Guangxi Province

(The advance publishing of the abstract of this manuscript does not mean final published, the end result whether or not published will depend on the comments of peer reviewers and decision of our editorial board.)
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